undiagnosed ktten fever

[Marcia]

I have a 9 week old male kitten that has had a fever for the last 3 weeks. It was removed from a hosehold that was infested with fleas. In fact on of the litter mates had a blood transfusion. She and the other litter mate are doing fine. This little one (weighing 1 lb. 11 oz.) started with a fever after it was put on Clavamox. At one point the fever was up to 105.5. He has been tested for feline leukemia twice and it was negitive. Was also tested for feline aids. That also was negitive. Now the kitten is not in my care but the person caring for him told me it was tested for hemobartonella and that was also negitive. She knew exactly what that was and said they did one blood test and said it was negitive. This lady also told me they did a ultra sound and it had a enlarged spleen. The kitten is now off antibiotics (because it did not help the fever) and is in strict quarinteen. We do have his litter mates in another cage near him. Other wise he is eating, is alert, still gaining some weight (never lost any, just never gained much), his eyes are clear (no mucus), noise is clean, seems to be breathing ok. He ran a fever again today. Any ideas what could be his problem?

[Traci]

Was a urinalysis done? Did the CBC show indications of elevated white blood cell counts? Were or are there NO accompanying symptoms? (i.e, vomiting, diarrhea, distended abdomen, weakness, etc)... Is liver function normal? If the ultrasound showed an enlarged spleen, was an aspirate done for cytology? (ultrasound-guided needle biopsy)

There are various causes to an enlarged spleen, first thing would be to get a full feline serology to rule out all forms of virals, blood-borne parasites, FIP, lupus, etc.....and consider differentials like heartworm, fibrosarcoma, heart problems, bacterials or mycobacterias.

If by chance your vets are saying remove the spleen, don't proceed until all differentials are completely ruled out (or else in event of life-saving procedure).

Any further information you can provide would be of help...